The rail union, which represents many members both at Avanti and Network Rail, has described this morning’s incident as “troubling” and a “highly serious matter”.
The group is calling for a thorough investigation in the days and weeks ahead.
TSSA General Secretary, Maryam Eslamdoust said: “The derailment of the Avanti West Coast train near Shap is very serious and will require thorough investigation.
“It’s always troubling and extremely dangerous when a train leaves the track under any circumstances, so it is right that a major incident has been declared.
“Thankfully it seems there and no major injuries and we thank the emergency services, including British Transport Police, for all they are doing for those who were on board.”